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Bisphenol A - the new silent killer? (link) :
Antidote Europe has launched a public campaign regarding the dangers of bisphenol A and has duly informed the new president of the European Parliament.

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We are asking the European Commission to implement toxicogenomics in replacement of toxicological tests on animals

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We are asking the European Commission to implement toxicogenomics in replacement of toxicological tests on animals. If you are a board member of an association, you can participate by signing our letter and joining all the associations that have already signed.
(Sign and send before 10 July 2006!)

Antidote Europe is a scientific committee willing to contribute to the blooming of an efficient and safe biomedical research. In spite of research's dynamism at the international level, the number of individuals suffering from severe diseases is increasing. It is about time to expose the defaults of the most usual techniques, largely based on animal experimentation, and to inform the public, the media and the authorities about the existence of safe methods, at the top of today's biomedical research, for example, toxicogenomics, of which we propose an original approach.

Why Antidote Europe ?

In spite of the increasing amount of specialised or popularised scientific published works, in spite of constant appeals through the media, for biomedical research, and testifying how dynamic this research is and how important its supplies, one cannot but state that the number of persons suffering from serious diseases in developing countries (in the very places where these means are used) is constantly growing.

As a major cause to this paradox, Antidote Europe has recorded the enduring of old-aged and outdated research methods with an efficiency which has never been proved, as a reference to animal experimenting, especially.

Since its beginning, this practice has been in dispute, but gained on at large from the end of the nineteenth century and was made compulsory, in some cases, in the first half of the twentieth century, under the pressure of its advocates, in spite of some raising and sometimes famous voices which have been opposed to it for ethical or scientific reasons ever since.

Antidote Europe doesn't aim at getting involved into the ethical issue over animal rights.

Antidote Europe is a scientific committee

Our committee is opposed to animal experimenting strictly for scientific reasons. Our president and a great number of our members are international researchers, so we can rightfully express ourselves thereon. That's why Antidote Europe exists: first to inform about the harm done because of this method on human health and the environment, then to promote true scientific methods.

The danger lies in the fact that the results of animal experimenting are not transposable to the human being, neither are they transposable between animal species. As a consequence, when a therapy is thoroughly tried and tested, when you test how efficient a medicine is, when the toxic risk of a chemical product is tested on a great number of guinea-pig animals, we are not at all informed about the effects of this therapy, medicine or product on human beings. Some ten thousands of chemical products are used, some are assessed as non toxic on the grounds of animal testing, others without any assessment. And we know that some harmless substance (or thought to be so) for some animal species or others is not necessarily harmless for humans.

Therefore we are guinea pigs just as animals. We can draw several consequences from this statement: side effects from medicines which range among the major causes for death in industrialised countries, the exponential increasing of death by cancer to be related to the amount of carcinogenic chemical substances to be found in one blood sample of any European or North American inhabitant, the increasing of cases suffering from neurological diseases (Alzheimer, Parkinson, multiple sclerosis, etc.), the growing of male sterility, etc.

In favour of a responsible science

Yet, there are some reliable methods to assess the toxicity of chemical matters. They are easy to carry out, less expensive than animal experimenting and the results are available in a few days only. Why aren't they imposed to industrials? That's what Antidote Europe is asking the authorities for.

When you know that a very product can be said harmless or carcinogenic according to the kind of animal species on which it's tested, it's obvious that animal experimenting is a precious tool to get the permission to bring even dangerous products on to the market, or to put victims who would try to sue the manufacturer off side. With a view to making financial profits, this method is clearly reliable! To the cost of public health and the environment.

Antidote Europe wishes to put the persons in charge of private or state-owned research centres face to face with their responsibilities in degrading human health, in polluting (still reversibly?), in killing uselessly animals in laboratories.

Antidote Europe wishes to denounce the accommodating of national and European authorities with chemical corporations and demand that the human health shouldn't be given up to industrial profits.

Why "Antidote" and "Europe"?

"Antidote" because it's still time for reacting, although everybody is already running some risks because of some ten thousands of chemical molecules to be found around us. The solution, acting in some way as a counter-poison, consists in testing the toxicity of these substances, on a reliable basis and in prohibiting the most dangerous ones. Thanks to our Scientific Toxicology Programme, the solution is partly under way.

"Europe" because molecules have no barriers and pollution is all around the world. Before creating "Antidote International", it appeared as a necessity to be of an influence outside France and to address the European Establishment for its decisions now influence the national laws. This seems workable as a purpose all the more so as our president is also the science adviser for an English organisation (Europeans for Medical Progress) and is in touch with numerous organisations inside and outside our country.

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Our team

Antidote Europe is run by Claude Reiss, our President, Augustine Savy, our secretary and Françoise Reiss, our paymaster.

Trained as a physician, Claude Reiss graduated at San Diego's university, California. On his way back to France, at the time when Jacques Monod and François Jacob had just been awarded the Nobel Prize for their research on the genetics of bacteria, he got interested in this dawning field and in biology at large.

His first works were dedicated to biophysics. He then involved himself into molecular biology and later on in toxicology. His research focused on two major fields:

- the protein translation and folding mechanism: this topic led him to build some hypothesis about the possible origins of such neurological diseases as Alzheimer, Parkinson, Creutzfeldt-Jakob (the corresponding human disease for the mad cow ), multiple sclerosis, etc.

- the aids virus and its reproducing strategy: with this topic Claude Reiss was led to propose an outcoming healing strategy. This technique has already been patented in the United States. The preclinical tests haven't been carried out yet and Claude Reiss is trying to gather all the money necessary to achieve them.

During more than thirty years, Claude Reiss worked as a research director, in the C.N.R.S. (the National Centre for Scientific Research in France) and at Jacques Monod's Institute. He also taught biology for third stage studies at Lille's University. Being now retired from public institutes, he's still doing his research within some private or associative structures.

He was a leading actor in the organization of two European workshops on cellular and molecular toxicology: one in Sophia Antipolis, in 1996, the other in Paris in 1999. The latter led to the publishing of the following book: Molecular Responses to Xenobiotics, under the direction of G. Labbe, H. Parvez, S. Parvez et C. Reiss (Ed Elsevier, 2001).

Augustine Savy was director's assistant, she is retired now. She was among the first to become members of Antidote Europe and she is actively dedicated to promote our association.

Françoise Reiss is an emeritus research director in the C.N.R.S. She is also an international specialist for bacterial photosynthesis.

With more than 150 written articles, she proved how the photosynthesis apparatus could turn the energy from light into chemical energy that is vital for the cell .She was the pioneer in building this apparatus architecture, which was a technical achievement as well as a decisive breakthrough in understanding photosynthesis.

Hélène Sarraseca, Antidote Europe's executive director and also co-founder, is in charge of the connections between members, the administration, together with the making of the quarterly journal, La Notice d'Antidote, and the scientific popularization.

Graduated in neurosciences, she kept research terms at the C.N.R.S. Not wishing to work in animal experimenting, she didn't take a PhD and accepted a job as a scientific competitive intelligence responsible in a company for biotechnology where she had several other positions (such as patent administrator) till the point when the company gave up business, as it was taken over by a laboratory in pharmaceutics.

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We are asking the European Commission to implement toxicogenomics in replacement of toxicological tests on animals. If you are a board member of an association, you can participate by signing our letter and joining all the associations that have already signed.
Sign before 10 July 2006!

Scientific research without animal experiments would allow to find therapeutic solutions relevant for humans, would allow a reliable assessment of chemical's toxicity. Whether your concern is for your health and that of your children, animal's welfare or Earth's pollution, let's work together !

En vous remerciant pour votre attention,
Bien cordialement,

Hélène Sarraseca
Directrice / Director

Antidote Europe
26 rue de Cernay - 91470 Les Molieres - France
0033 (0)1 45 77 48 15 (lundi et jeudi de 10h30 à 18h / Monday and Thursday
from 10h30 to 18h)